Clothianidin 25% + Fludioxonil 1.5% + Prothioconazole 3% FS

Product Attribute	Specification
Product Name	Clothianidin 25% + Fludioxonil 1.5% + Prothioconazole 3% FS
Clothianidin Content	25%
Fludioxonil Content	1.5%
Prothioconazole Content	3%
Total Active Content	29.5%
Formulation	FS — Flowable Concentrate for Seed Treatment
Product Type	Insecticide + fungicide seed treatment
Clothianidin IRAC Group	Group 4A
Fludioxonil FRAC Group	Group 12
Prothioconazole FRAC Group	Group 3
Primary Disease Direction	Fusarium, Rhizoctonia, seed rot and seedling diseases where registered
Primary Insect Direction	Early sucking pests and approved soil insects
Main Crop Direction	Cotton and other approved field crops
Application Stage	Pre-sowing seed treatment
Standard MOQ	Normally 1,000 L
Available Documents	COA, SDS, TDS, product specification and available registration-supporting information
Supply Type	Bulk B2B supply for registration, import and distribution

Final crops, target diseases, insects, application rates, slurry volumes, treated-seed storage periods and planting restrictions must follow the approved destination-market label.

What Is Clothianidin + Fludioxonil + Prothioconazole FS?

This formulation combines two fungicide modes of action with one systemic insecticide in a professional seed-treatment product.

Its main purpose is to protect the seed and developing seedling during crop establishment.

Potential protection directions include:

• Fusarium-related seed and seedling diseases
• Rhizoctonia-related seedling diseases
• Seed rot
• Seedling blight
• Aphids
• Thrips
• Wireworms
• White grubs
• Other approved early-season insects

The product is designed for pre-sowing seed treatment.

It should not be treated as a foliar fungicide, late-season insecticide or universal soil-pest product.

Why Combine These Three Active Ingredients?

Seedling establishment can be affected simultaneously by fungal infection and insect feeding.

This formulation combines three different functions in one treatment.

Protective Seed-Surface Fungicide

Fludioxonil remains concentrated around the treated seed and immediate seed zone.

It provides early protective activity against susceptible fungi before and during germination.

Systemic Seedling Fungicide

Prothioconazole adds a different fungal mode of action and systemic disease-protection profile.

This broadens the fungal component beyond surface protection alone.

Systemic Insect Protection

Clothianidin is absorbed by the developing plant and provides early activity against approved sucking and soil insects.

The three active ingredients therefore address two planting-stage risk categories:

fungal disease pressure and early insect pressure.

They should not be described as three active ingredients attacking every target simultaneously.

How Do the Three Active Ingredients Work?

Fludioxonil — FRAC Group 12

Fludioxonil belongs to FRAC Group 12, the phenylpyrrole fungicides.

It affects fungal osmotic signal transduction and cellular regulation in susceptible pathogens.

In a seed-treatment program, Fludioxonil is mainly valued for activity around:

• The treated seed coat
• The immediate seed zone
• Germinating seed
• Early infection sites

Typical disease directions may include:

• Seed rot
• Seedling blight
• Fusarium-related seed diseases
• Rhizoctonia-related diseases
• Alternaria-related seed infection
• Other registered seed- and soil-borne fungi

Fludioxonil should not be described as moving extensively throughout the entire seedling.

Prothioconazole — FRAC Group 3

Prothioconazole belongs to FRAC Group 3 and is a DMI fungicide.

It inhibits sterol biosynthesis in susceptible fungi by interfering with the CYP51-related demethylation process.

Sterols are important components of fungal cell membranes. Disruption of their formation restricts fungal development and infection.

In seed treatment, Prothioconazole may provide activity against registered:

• Fusarium species
• Rhizoctonia species
• Seedling blights
• Seed-borne fungal diseases
• Bunt and smut diseases where specifically registered
• Other susceptible seedling pathogens

Its main role is to extend the formulation from seed-surface protection into systemic seedling disease management.

Clothianidin — IRAC Group 4A

Clothianidin belongs to IRAC Group 4A, the neonicotinoid insecticides.

It acts on insect nicotinic acetylcholine receptors and disrupts normal nerve signaling.

When used as a seed treatment, Clothianidin may be absorbed by germinating seedlings and distributed into young plant tissues.

Typical target directions may include:

• Aphids
• Thrips
• Flea beetles
• Wireworms
• White grubs
• Other approved soil insects
• Other early-season sucking pests

The duration of protection depends on crop, rate, pest pressure, growing conditions and registration.

It should not be promoted as providing full-season insect control.

Combined Seed Protection Profile

The three active ingredients have clearly separated roles.

Planting-Stage Risk	Main Active Contribution
Seed-surface fungal infection	Fludioxonil
Fusarium and related seedling diseases	Prothioconazole + Fludioxonil contribution
Rhizoctonia-related seedling disease	Prothioconazole + Fludioxonil contribution
Early sucking insects	Clothianidin
Soil insects	Clothianidin
Combined disease and insect pressure	Three-active FS formulation

This fixed combination can simplify commercial seed-treatment programs where both early fungal disease and insect pressure are relevant.

Main Disease and Pest Directions

The following table describes typical market positioning and does not represent a universal registration label.

Protection Direction	Typical Target	Product Positioning
Fusarium Seedling Disease	Susceptible Fusarium species	Core fungal disease direction
Rhizoctonia Seedling Disease	Susceptible Rhizoctonia species	Early root and seedling protection
Seed Rot	Registered seed-borne fungi	Fludioxonil-led protection
Seedling Blight	Approved fungal pathogens	Early establishment protection
Aphids	Registered early sucking pests	Systemic Clothianidin activity
Thrips	Approved early thrips species	Seedling-stage insect protection
Wireworms	Registered soil insects	Seed and root-zone protection
White Grubs	Approved scarab larvae	Soil-insect direction
Other Early Insects	Crop-specific pests	Registration-dependent

Exact claims must match the local registration and efficacy data for this 29.5% FS formulation.

Cotton Seed Treatment

Cotton is a strong commercial positioning direction for this product where the formulation is registered.

Seedlings can face both fungal disease and insect pressure during emergence and early establishment.

Fusarium and Seedling Disease Protection

Potential fungal directions may include:

• Fusarium-related seedling disease
• Seed rot
• Seedling blight
• Early root infection
• Other approved fungal diseases

Fludioxonil protects the treated seed and immediate seed environment, while Prothioconazole adds systemic FRAC Group 3 activity.

Rhizoctonia Disease Protection

Rhizoctonia may contribute to:

• Pre-emergence seedling loss
• Post-emergence damping and blight
• Root damage
• Stem-base infection

This product may be positioned against Rhizoctonia-related cotton seedling diseases where supported by registration.

It should not be assumed to control every cause of damping-off because similar symptoms may be caused by other pathogens.

Early Sucking Pest Protection

Clothianidin may provide early systemic protection against approved:

• Aphids
• Thrips
• Flea beetles
• Other sucking pests

Early control can help reduce feeding pressure during a crop stage when young plants are particularly vulnerable.

Later pest populations still require field scouting.

Soil Insect Protection

Depending on the local registration, the product may also be positioned against:

• Wireworms
• White grubs
• Other soil-feeding insects

Performance depends on pest species, population, planting conditions and application rate.

Other Approved Field-Crop Seed Programs

The same formulation may be considered for other field crops where specific registration supports the use.

Potential crop directions may include:

• Wheat
• Barley
• Maize
• Legumes
• Other approved field crops

However, the exact disease and insect complex should determine product selection.

For cereal seed programs focused more specifically on bunt, Fusarium and early cereal insects, buyers can review the POMAIS Difenoconazole + Thiamethoxam + Fludioxonil FS.

What This Product Does Not Automatically Cover

A professional seed-treatment page should clearly define the formulation limits.

Pythium and Phytophthora

This formulation does not contain a dedicated Oomycete-active seed-treatment ingredient such as Metalaxyl-M.

Pythium and Phytophthora should only be claimed where the exact product registration supports those diseases.

For Oomycete-focused seed programs, see the POMAIS Fludioxonil + Metalaxyl-M + Thiamethoxam FS.

Late-Season Foliar Diseases

This product is formulated for seed treatment.

The presence of Prothioconazole does not mean that the FS product should be used as a foliar cereal or field-crop fungicide.

POMAIS also offers Prothioconazole 480 g/L SC for separately registered foliar disease programs.

Late-Season Insects

Clothianidin seed treatment is mainly positioned for early crop establishment.

It should not replace later monitoring or foliar insecticide decisions.

Nematodes

The formulation should not be described as a nematicide unless the exact local registration includes that claim.

Bacterial and Viral Diseases

The product does not directly control bacterial or viral pathogens.

Control of insect vectors should not be described as direct virus control.

Plant Growth Regulation

The formulation is not a plant growth regulator.

Do not claim guaranteed improvements in germination, root development, plant height or yield without product-specific trial data.

Professional Seed Treatment Process

1. Confirm the Crop and Registration

Before treatment, verify:

• Crop
• Seed variety
• Registered disease
• Registered insect
• Application rate
• Slurry volume
• Planting instructions
• Treated-seed restrictions

2. Inspect Seed Quality

Use seed that meets the required standards for:

• Germination
• Vigor
• Moisture
• Purity
• Physical integrity

Cracked, overheated, wet or low-vigor seed may respond differently to treatment.

3. Calibrate the Seed Treater

Commercial equipment should provide the correct volume per unit of seed.

Calibration should be reviewed when:

• Seed size changes
• Seed lot changes
• Treatment rate changes
• Equipment is adjusted
• Product temperature or viscosity changes

4. Prepare the Treatment Slurry

Where dilution is required, use clean water and the approved slurry volume.

Maintain sufficient agitation to keep all three active ingredients uniformly distributed.

5. Achieve Uniform Seed Coverage

A professional coating should minimize:

• Untreated seed surfaces
• Excess product accumulation
• Uneven coloration
• Over-wetting
• Active ingredient variation between seeds

6. Allow Appropriate Drying

Treated seed should dry according to the validated commercial process.

Correct drying supports:

• Seed flowability
• Packaging
• Transport
• Planting
• Reduced coating loss

7. Handle Treated Seed Correctly

Keep treated seed clearly identified and separated from untreated seed.

Treated seed must not be used for food, animal feed or other unapproved purposes.

FS Formulation and Seed-Coating Performance

FS means Flowable Concentrate for Seed Treatment.

It is specifically developed for commercial application to seed before planting.

Uniform Seed Coverage

Coverage quality affects how evenly the active ingredients are delivered across the seed lot.

Important factors include:

• Product viscosity
• Particle size
• Seed shape
• Slurry volume
• Equipment calibration
• Mixing time
• Seed moisture

Adhesion

After drying, the treatment should remain sufficiently attached to the seed.

Good adhesion helps reduce product loss during:

• Bagging
• Transport
• Seed transfer
• Planter loading

Dust-Off Control

Treated-seed dust is an important stewardship and worker-exposure consideration.

Commercial formulation development should aim to minimize dust-off without claiming that treated seed is completely dust-free.

Drying and Seed Flowability

Poor drying may cause:

• Seed clumping
• Equipment blockage
• Uneven planting
• Coating loss
• Packaging contamination

The correct balance between adhesion and flowability is an important FS quality parameter.

Key FS Quality Parameters

Quality Parameter	Buyer Relevance
Clothianidin Assay	Confirms the declared 25% content
Fludioxonil Assay	Confirms the declared 1.5% content
Prothioconazole Assay	Confirms the declared 3% content
Three-Active Uniformity	Maintains the correct fixed ratio
Physical Appearance	Detects settling, separation or crystallization
Suspensibility	Supports uniform treatment slurry
Particle Size	Influences coating and equipment performance
Wet Sieve Residue	Helps prevent pipe and nozzle blockage
Viscosity	Influences pumping and metering
Pourability	Supports commercial handling
Redispersibility	Confirms recovery after storage
pH	Supports formulation stability
Persistent Foam	Influences seed-treatment equipment
Seed Adhesion	Measures coating retention
Dust-Off	Evaluates particulate release
Drying Behavior	Supports processing efficiency
Seed Flowability	Supports packaging and sowing
Germination Compatibility	Confirms crop tolerance at the registered rate
Cold and Heat Stability	Supports export storage and shipping
Packaging Compatibility	Supports long-term product integrity

For B2B buyers, three-active uniformity and seed-coating performance are as important as active ingredient concentration.

Seed Safety and Germination Compatibility

Correct seed treatment should protect the seed without causing unacceptable crop injury.

Important factors include:

• Seed moisture
• Seed vigor
• Variety
• Treatment rate
• Slurry volume
• Drying conditions
• Polymer use
• Additional treatment products
• Storage after treatment
• Planting conditions

Avoid Over-Treatment

Increasing the application rate does not guarantee better control.

Excess treatment may increase:

• Seed wetness
• Drying time
• Coating instability
• Crop-injury risk
• Active ingredient loading
• Dust-off

Germination Evaluation

New seed lots, varieties or treatment combinations may require testing for:

• Germination
• Seedling emergence
• Seedling vigor
• Root growth
• Coating integrity

Do not use general claims such as “improves germination” without formulation-specific evidence.

Treated-Seed Storage

Product shelf life and treated-seed storage stability are different.

After seed is treated, its germination and coating quality may change over time.

Important factors include:

• Seed moisture
• Storage temperature
• Storage duration
• Treatment rate
• Coating polymer
• Packaging conditions

Commercial programs intending to store treated seed should verify germination and vigor after the planned storage period.

Treated seed should not be assumed to remain suitable indefinitely.

Resistance Management

This product contains two fungicide groups and one insecticide group.

Fungicide Resistance

Fludioxonil belongs to FRAC Group 12.

Prothioconazole belongs to FRAC Group 3.

The two mechanisms provide complementary disease protection, but the formulation is not resistance-proof.

Later crop protection programs should consider total exposure to these mode-of-action groups.

Other Group 3 fungicides include:

• Difenoconazole
• Tebuconazole
• Propiconazole
• Myclobutanil
• Other DMI fungicides

Changing from Prothioconazole to another Group 3 active ingredient does not represent a complete mode-of-action change.

Insecticide Resistance

Clothianidin belongs to IRAC Group 4A.

Other Group 4A insecticides include:

• Thiamethoxam
• Imidacloprid
• Acetamiprid
• Dinotefuran

Changing only between these active ingredients should not be treated as a full resistance rotation.

Integrated Program Principles

Seed treatment should be combined with:

• Resistant or tolerant varieties where available
• High-quality seed
• Crop rotation
• Field sanitation
• Pest monitoring
• Disease scouting
• Effective alternative modes of action
• Responsible foliar treatment

Treated Seed Safety and Environmental Precautions

Not for Food or Feed

Treated seed must not be used for:

• Human food
• Animal feed
• Oil processing
• Food processing
• Any unapproved purpose

Worker Protection

Operators should follow the final SDS and local label during:

• Mixing
• Seed treatment
• Equipment cleaning
• Packaging
• Seed transfer
• Planting

General precautions may include:

• Protective clothing
• Chemical-resistant gloves
• Eye protection
• Respiratory protection where required
• Dust-control procedures
• Washing after handling

Spilled Seed

Spilled treated seed should be collected where practical.

Do not leave treated seed exposed where:

• Birds
• Wildlife
• Livestock
• Non-target animals

may consume it.

Disposal

Unused treated seed, containers and treatment waste should be handled according to local regulations.

Product Storage

Store Clothianidin 25% + Fludioxonil 1.5% + Prothioconazole 3% FS:

• In the original sealed container
• In a cool and dry warehouse
• Away from direct sunlight
• Away from excessive heat
• Away from freezing where relevant
• Away from food and animal feed
• Away from children and unauthorized persons
• Under the conditions stated in the final SDS

Before shipment, inspect:

• Bottle condition
• Cap security
• Seal integrity
• Product homogeneity
• Label accuracy
• Batch coding
• Fill volume
• Carton strength
• Pallet stability

Comparison with Other POMAIS Seed Treatments

Different formulations should be selected according to the actual crop, disease and pest complex.

Seed Treatment	Best-Fit Positioning
Fludioxonil + Metalaxyl-M + Thiamethoxam FS	Oomycete diseases + seed fungi + early insects
Difenoconazole + Thiamethoxam + Fludioxonil FS	Cereal bunt/Fusarium + early cereal insects
Fludioxonil + Thifluzamide + Clothianidin FS	Rhizoctonia/sharp eyespot + early insects
Clothianidin + Fludioxonil + Prothioconazole FS	Fusarium/Rhizoctonia seedling diseases + early insects in cotton and approved field crops
Insecticide-Only FS	Early insect protection without fungicide activity
Fungicide-Only FS	Seed and seedling disease protection without insecticide activity

This allows importers and distributors to build a seed-treatment portfolio based on target risk, rather than simply comparing total active ingredient concentration.

Packaging, Quality Control and Documentation

POMAIS supplies Clothianidin 25% + Fludioxonil 1.5% + Prothioconazole 3% FS for qualified importers, distributors, registration companies and agricultural brands.

Packaging Options

Potential commercial packaging may include:

• 100 mL bottles
• 250 mL bottles
• 500 mL bottles
• 1 L bottles
• 5 L containers
• 10 L containers
• 20 L containers
• Larger commercial packs where suitable
• Tamper-evident closures
• Multilingual labels
• Retail cartons
• Export cartons
• Batch and expiry coding
• Shipping marks

Final packaging depends on registration, order quantity and seed-treatment equipment requirements.

Quality-Control Focus

Commercial batch testing may include:

• Clothianidin content
• Fludioxonil content
• Prothioconazole content
• Three-active uniformity
• Physical appearance
• Suspensibility
• Particle size
• Wet sieve residue
• Viscosity
• Pourability
• Redispersibility
• pH
• Persistent foam
• Seed adhesion
• Dust-off
• Drying behavior
• Seed flowability
• Germination compatibility
• Cold stability
• Heat stability
• Packaging compatibility
• Fill-volume accuracy
• Batch consistency

Available Documents

Document support may include:

• COA — Certificate of Analysis
• SDS — Safety Data Sheet
• TDS — Technical Data Sheet
• Product Specification
• Packaging Specification
• Available Seed-Coating Performance Data
• Available Germination Compatibility Data
• Available Efficacy Information
• Available Crop-Safety Information
• Available Storage-Stability Information
• Available Registration-Supporting Information
• Batch-Related Quality Documents
• Commercial and Shipping Documents

Frequently Asked Questions

What is Clothianidin 25% + Fludioxonil 1.5% + Prothioconazole 3% FS used for?

It is a pre-sowing seed treatment combining fungal disease protection with systemic early-season insect control.

Typical directions include Fusarium, Rhizoctonia, seedling disease and approved early sucking or soil insects.

Is this product an insecticide or a fungicide?

It is both.

Clothianidin is an insecticide, while Fludioxonil and Prothioconazole are fungicides.

What FRAC group is Fludioxonil?

Fludioxonil belongs to FRAC Group 12.

What FRAC group is Prothioconazole?

Prothioconazole belongs to FRAC Group 3.

What IRAC group is Clothianidin?

Clothianidin belongs to IRAC Group 4A.

Can it control Fusarium seedling diseases?

It may be positioned against registered Fusarium seed and seedling diseases.

Exact claims depend on the crop and product registration.

Can it control Rhizoctonia?

Rhizoctonia-related seedling diseases may be important product directions where supported by the label.

Can it protect seedlings from aphids?

Clothianidin may provide systemic early-season aphid protection where the target crop and pest are registered.

Can it control thrips?

Early thrips may be included in some registered seed-treatment programs.

The exact pest species and duration of protection must follow the local label.

Can it control wireworms or white grubs?

These may be relevant Clothianidin soil-insect directions where the exact registration supports them.

Is it suitable for cotton seed treatment?

Cotton is an important commercial positioning direction where the product is registered for the crop.

Does it control Pythium or Phytophthora?

These Oomycete diseases should not be claimed automatically.

The formulation does not contain a dedicated Oomycete-active ingredient such as Metalaxyl-M.

Can it be used as a foliar spray?

No general foliar use should be assumed.

FS means Flowable Concentrate for Seed Treatment and is designed for pre-sowing application.

Does it improve germination?

No universal germination-improvement claim should be made.

The product should instead be evaluated for germination compatibility and seedling safety at the registered rate.

Can treated seed be stored?

Storage may be possible where supported by crop-specific treated-seed stability data.

Do not assume that treated seed can be stored for the same period as the unopened FS product.

Can it be mixed with other seed treatments?

Only where physical compatibility, seed coating, crop safety and biological performance have been confirmed.

What packaging is available?

Potential package sizes include 100 mL, 250 mL, 500 mL, 1 L, 5 L, 10 L and 20 L.

Final packaging depends on registration and commercial requirements.

What is the minimum order quantity?

The standard minimum order quantity is normally 1,000 L.

Request Product Specifications

To evaluate a Clothianidin 25% + Fludioxonil 1.5% + Prothioconazole 3% FS purchasing or registration project, please provide:

• Destination country
• Company type
• Required quantity
• Preferred package size
• Target crop
• Target seed or seedling diseases
• Target early-season insects
• Seed-treatment equipment
• Required slurry volume
• Current registration status
• Required label language
• Required technical documents
• Expected purchasing schedule

We will review the three-active specification, FS coating performance, seed compatibility, packaging feasibility and destination-market requirements before confirming the commercial proposal.

Clothianidin 25% + Fludioxonil 1.5% + Prothioconazole 3% FS is supplied for professional seed treatment, B2B procurement, registration and wholesale distribution.