Bifenazate Insecticide & Acaricide

Mode of Action

Bifenazate belongs to IRAC Group 20D and is classified as a mitochondrial Complex III electron transport inhibitor.

The mitochondrial electron transport process is involved in cellular energy metabolism. Bifenazate’s mode of action involves interfering with electron transport in mitochondrial Complex III, thereby disrupting the normal physiological activities of susceptible mites.

IRAC Group 20D — Bifenazate

IRAC Group 20D is the specific classification of Bifenazate’s mode of action. When evaluating a portfolio of acaricides, purchasers should use the IRAC classification to identify the relationships between the modes of action of different active ingredients.

Different trade names, concentrations, or formulations do not necessarily imply different modes of action. Therefore, when developing resistance management strategies, attention should be focused on the IRAC Group corresponding to the active ingredient, rather than simply comparing product names.

Contact Activity and Spray Coverage

Bifenazate is typically used as a non-systemic foliar acaricide. For formulations that rely on contact activity, the quality of spray coverage is a critical factor affecting control efficacy.

Insufficient coverage of both sides of the leaves, overly dense plant canopies, or inadequate coverage of areas where target mites are hiding may all affect actual control efficacy. Specific application methods should follow the instructions on the product label and the requirements of the applicable application equipment.

Bifenazate should not be described as having unproven systemic translocation capabilities, nor should its non-systemic nature alone be used to infer that the risk of drift or off-target exposure is necessarily low.

Recommended Crops and Target Mites

Publicly available product labels and technical data for Bifenazate provide application guidance for certain fruit trees, berry crops, fruiting vegetables, and ornamental plants.

The table below is intended to assist importers and distributors in evaluating candidate crop markets. It is not a comprehensive list of all Bifenazate formulations listed in POMAIS. Specific crops, target mites, and application methods must be verified on a case-by-case basis based on the actual formulations available and the approved labels for the target markets.

Primary Crop Opportunities

Candidate Crops	Candidate Target Mites	Key Product Evaluation Points
Apple	European Red Mite, Spider Mites	Verify fruit tree registrations and target mite species for specific formulations
Citrus	Citrus Red Mite, other Spider Mites supported by data	Verify citrus species, mite species, and local registrations
Grapes	Spider Mites	Verify the specific formulation’s use on grapes
Berries	Spider Mites	Confirm based on specific berry crops and label
Tomato	Two-Spotted Spider Mite and other applicable leaf mites	Verify scope of use (field or greenhouse) and crop safety
Other Fruiting Vegetables	Certain Spider Mites	Evaluate based on specific crops and approved labels
Ornamentals	Certain Spider Mites, Red Mites	Verify specific ornamental plants and applicable labels

Target Mite Species and Life Stages

The scope of control for Bifenazate must be specified in terms of mite populations and life stages; it must not be generally promoted as capable of controlling all phytophagous mites.

Some publicly available product labels describe Bifenazate’s primary mode of action as targeting active mites and note that it exhibits ovicidal activity against the eggs of certain leaf mites in the genus Tetranychus.

However, this characteristic cannot be generalized to imply efficacy against all mite eggs, all developmental stages, or all mite species. For targets such as Broad Mites, Flat Mites, and Rust Mites, claims that they are effectively controlled by this product should be avoided in the absence of clear product-level evidence.

How to Confirm Crop Suitability

Before formally recommending a crop, the following should be verified on a case-by-case basis:

• Crop Registration: Is the target crop included in the approved scope of use for the specific formulation?
• Target Mite: Does the label explicitly list the corresponding mite species, or is there reliable product-level data to support this?
• Formulation Suitability: Are the current concentration and formulation suitable for the intended application method?
• Crop Safety: Is there corresponding crop safety data available?
• Residue Requirements: Does the product meet the Maximum Residue Limits (MRLs) and pre-harvest intervals required by the target market?

To assess pest mite management needs on other crops, refer to POMAIS Crop Pest Management Solutions.

Formulation Options and Quality Requirements

The actual performance of bifenazate products depends not only on the active ingredient but also on formulation design, granule characteristics, quality control, and storage conditions.

Formulation	Product Form	Key Procurement Review Points
22.6% SC	Suspension Concentrate	Suspension Performance, Dispersibility, Storage Stability
24% SC	Suspension Concentrate	Active ingredient content, suspension performance, and batch consistency
48% SC	Suspension Concentrate	Actual content, formulation quality, and corresponding product documentation
50% WP	Water-dispersible powder	Wettability, suspension properties, wet sieving performance, and packaging suitability
50% WDG	Water-dispersible granules	Disintegration, suspension properties, wet sieving performance, and storage stability

Before formal release or quotation, please confirm the actual available specifications, corresponding technical specifications, and suitability for the target market.

SC Formulation

SC (Suspension Concentrate) consists of solid active ingredient particles dispersed in a liquid phase. Buyers should focus on indicators such as active ingredient content, suspension performance, wet sieving performance, sustained foaming, pourability, and storage stability.
Claims regarding faster knockdown speed, a fixed residual efficacy period in the field, or absolutely no settling should not be made based solely on the SC formulation name.

WP and WDG Formulations

WP (Wettable Powder) and WDG (Water-Dispersible Granule) differ in physical form, formulation process, and quality specifications.

For WP, verification should focus on wetting, suspension, and related quality specifications; for WDG, verification should focus on granule disintegration, dispersion, suspension, and wet sieving performance.

Quality requirements for different formulations must be based on the corresponding product specifications and applicable standards; test results for one formulation cannot be directly applied to another.

Application Guidelines

The application rate, timing, and frequency of Bifenazate depend on the specific concentration, formulation, crop, target mites, and locally approved label.

Application Parameters to Confirm

Application Parameters	Confirmation Requirements
Target Crop	Refer to the approved label for the corresponding product
Target Mite	Refer to the registered target pests
Application Rate	Confirm based on specific concentration, formulation, and label
Application Method	Follow the application method specified on the approved label
Spray Coverage	Confirm based on product instructions and applicable equipment requirements
Application Interval	Refer to the approved label
Maximum Applications	Follow label instructions
Pre-Harvest Interval (PHI)	Refer to the approved label for the target market
Re-Entry Interval (REI)	Refer to the approved label for the target market

Spray Coverage and Timing

For specific formulations applied via foliar spraying, ensure coverage of both the upper and lower surfaces of leaves, account for the plant canopy structure, and monitor the occurrence of target mites in accordance with label requirements.

Some publicly available labels for bifenazate products recommend prompt and appropriate control measures upon detection of mites; however, the actual application timing, dosage, and application intervals must follow the approved label for the specific product.

Application parameters from other countries, different concentrations, or other formulations must not be directly applied to this product.

Resistance Management

Bifenazate belongs to IRAC Group 20D. Long-term, repeated use of acaricides with the same mode of action may increase the selective pressure for target mites to develop resistance.

Key Resistance Management Principles

• Develop management strategies based on the target mites, local resistance status, and the approved label.
• Where appropriate, rotate the use of products with different modes of action that are effective against the target mites.
• Do not mistakenly assume that different trade names, concentrations, or formulations represent different modes of action.
• Do not assume that a mixed-formulation product offers independent resistance management advantages simply because it contains two active ingredients.
• Combine field monitoring, appropriate cultural practices, and other applicable mite management methods to reduce reliance on a single mode of action.

Bifenazate in Integrated Pest Management

Integrated Pest Management (IPM) requires a combination of mite monitoring, appropriate application strategies, cultural management, and assessment of risks to beneficial organisms.

Whether bifenazate is suitable for a particular IPM program should be determined based on the specific formulation, target mites, and conditions of use. It cannot be generally claimed to be safe for all predatory mites, parasitic wasps, and pollinating insects.

For greenhouse and orchard projects requiring coordination with biological control measures, it is recommended to first verify the specific product label and reliable data on non-target organisms before determining the application schedule.

Safety and Environmental Considerations

The safe management of bifenazate products should be based on the specific formulation’s SDS, approved label, and regulations of the target market.

Non-Target Organisms

Data on some bifenazate formulations indicate that this active ingredient can be used for selective mite management under specific conditions and can be incorporated into appropriate IPM programs. However, this does not mean that all formulations are free of impact on all beneficial organisms.

When evaluating products, focus on the following:

• Label warnings regarding bees and other non-target organisms.
• Risks of spray drift and exposure in non-target areas.
• Effects on beneficial organisms, such as predatory mites.
• Specific application restrictions when used in conjunction with other plant protection measures.

One should not infer that spray drift is minimal or that non-target risks are necessarily low solely based on the non-systemic nature of bifenazate.

Safe Handling and Storage

Purchasers should verify the actual product’s hazard classification, personal protective equipment (PPE), storage requirements, spill response procedures, and waste disposal requirements.

During operations, follow the environmental protection measures listed on the product label to prevent spray solution, washwater, or contaminated materials from entering rivers, ponds, drainage ditches, and other bodies of water.

Specific safety requirements should be based on the SDS and approved label of the actual supplied formulation; general information about the active ingredient cannot be directly used to draw comprehensive safety conclusions regarding the finished formulation.

Quality Control and Technical Documentation

For Bifenazate products, procurement audits should focus on product identity, active ingredient content, formulation quality, and batch traceability.

Quality Verification Checklist

Audit Items	Items to Verify
Product Identity	Consistency of active ingredient, content, and dosage form
Active Ingredient Content	Nominal content and batch test results
Formulation Quality	Quality specifications for the corresponding dosage form
Storage Stability	Stability data consistent with the actual product
Packaging Integrity	Packaging integrity and suitability of materials
Batch Traceability	Batch numbers and related production records
Quality Standard	Technical specifications of the actual product supplied

COA, SDS, and TDS

Purchasers may verify the following documents based on order requirements and target market specifications:

• COA (Certificate of Analysis): Test results for the corresponding batch.
• SDS (Safety Data Sheet): Information on product safety, storage, operational precautions, and emergency response.
• TDS (Technical Data Sheet): Product technical parameters and relevant quality specifications.
• Other technical or registration documents: To be confirmed based on the target market and actual availability.

All documents must be consistent with the actual product’s concentration, formulation, and quality standards. General technical documents cannot substitute for local registration nor serve as proof that the product has been approved for use on all candidate crops.

B2B Supply and Procurement: Commercial Procurement and Supply Partnerships

POMAIS offers specialized product supply partnerships to pesticide importers, distributors, brand owners, and registration companies.

For Bifenazate products, we recommend specifying the target country, required concentration, formulation, candidate crops, target mites, and estimated purchase quantity before requesting a quote, in order to confirm the actual available specifications and corresponding technical documentation.

Procurement Items	Information to Be Confirmed
Required Product	Bifenazate and required concentration, formulation
Destination Country	Target Import Country
Target Crops and Mites	Planned target crops and mites
Registration Status	Current registration status or plans
Packaging Requirements	Available packaging specifications and labeling requirements
Technical Documents	Requirements for COA, SDS, TDS, and other documents
Expected Purchase Volume	Estimated Purchase Quantity
Delivery Requirements	Estimated Delivery Arrangements and Terms of Trade

Packaging specifications, MOQ, delivery times, and technical documents should be confirmed based on actual supply availability, order quantity, and destination requirements. For registration documentation or multilingual labeling requirements specific to certain markets, the scope of feasibility should be clarified in advance.

If a buyer needs to evaluate formulation options combining Bifenazate with other active ingredients, the actual formulation, product specifications, quality data, and corresponding registration basis must be confirmed separately; unverified mixture formulations must not be sold as formal formulated products.

Frequently Asked Questions

What Is Bifenazate?

Bifenazate is a selective acaricide active ingredient primarily used for the management of certain phytophagous mites. Specific target pests and applicable crops should be confirmed based on the label and technical data of the actual formulation.

What Is the IRAC Group of Bifenazate?

Bifenazate belongs to IRAC Group 20D and is classified as a mitochondrial Complex III electron transport chain inhibitor.

Which Crops Can Be Considered for Bifenazate?

Priority should be given to evaluating candidate crops such as apples, grapes, citrus, berries, certain fruit and vegetable crops, and ornamental plants. Specific uses should be verified based on the labels approved for the actual formulations supplied and the target markets.

Which Mites Should Be Evaluated?

Priority should be given to evaluating certain spider mites, including the two-spotted spider mite, the European red mite, and other leaf mites supported by specific product data. Not all mite species can be listed as confirmed targets for control.

Does Bifenazate Control All Mite Life Stages?

This cannot be generalized. Some formulations primarily target active mites and are active against the eggs of certain leaf mites in the Tetranychus genus. The actual range of life stages covered should be determined by the corresponding product label and technical data.

Is Bifenazate a Systemic Acaricide?

Bifenazate is typically used as a non-systemic foliar acaricide. For specific formulations that act by contact, the quality of application coverage is a critical factor. Actual application practices should follow the corresponding product label.

What Is the Recommended Application Rate?

The application rate depends on the specific concentration, formulation, crop, target mites, and locally approved label.

Can Bifenazate Be Mixed with Other Pesticides?

Before mixing, verify the labels of both products, compatibility, crop safety, and usage restrictions. Physical compatibility testing does not replace verification of efficacy and crop safety, nor does it automatically prove that the mixture has value for resistance management.

What Documents Can Buyers Request?

Buyers may request a Certificate of Analysis (COA), Safety Data Sheet (SDS), Technical Data Sheet (TDS), and other relevant technical documents based on the specific product and target market requirements. The specific scope of documents to be provided should be verified prior to placing an order.

How Can Importers Request a Quotation?

Importers, distributors, brand owners, and registration companies may provide the target country, product concentration and formulation, candidate crops and target mites, registration status, estimated purchase quantity, and document requirements to confirm product supply terms.

Request Product Specifications and Quotation – Inquiries and Procurement Consultations

If you are evaluating Bifenazate products, we recommend providing the following information:

• Destination Country: Target import country.
• Required Specification: Required concentration and formulation.
• Target Crops and Mites: Crops and target mites for which the product is intended.
• Registration Status: Current registration status or plans.
• Packaging Requirements: Packaging specifications and labeling requirements.
• Expected Purchase Volume: Estimated purchase quantity.
• Technical Documents: Required COA, SDS, TDS, and other documentation.
• Delivery Requirements: Expected procurement and delivery arrangements.

POMAIS will further confirm the procurement cooperation plan based on actual product specifications, technical documentation, supply conditions, and target market requirements.